Rotavirus gene structure and function.
نویسندگان
چکیده
منابع مشابه
Rotavirus gene structure and function.
Knowledge of the structure and function of the genes and proteins of the rotaviruses has expanded rapidly. Information obtained in the last 5 years has revealed unexpected and unique molecular properties of rotavirus proteins of general interest to virologists, biochemists, and cell biologists. Rotaviruses share some features of replication with reoviruses, yet antigenic and molecular propertie...
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Of the six structural and six nonstructural proteins encoded by the segmented double-stranded (ds) R N A genome of the rotaviruses, recent studies suggest that as many as seven may have affinity for RNA. While their functions in virus replication have yet to be precisely defined, the RNA-binding proteins may play essential roles in a number of events including: (i) transport of viral m R N A s ...
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A ganglioside fraction isolated from pooled intestines from newborn to 4-week-old piglets, which we previously partially characterized and showed to specifically inhibit the binding of porcine rotavirus (OSU strain) to host cells (M. D. Rolsma, H. B. Gelberg, and M. S. Kuhlenschmidt, J. Virol. 68:258-268, 1994), was further purified and found to contain two major monosialogangliosides. Each gan...
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Rotavirus (RV)-infected piglets are presumed to be latent sources of heterologous RV infection in humans and other animals. In RVs, non-structural protein 4 (NSP4) is the major virulence factor with pleiotropic properties. In this study, we analyzed the nsp4 gene from porcine RVs isolated from diarrheic and non-diarrheic cases at different levels of protein folding to explore correlations to di...
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chapter one is devoted to a moderate discussion on preliminaries, according to our requirements. chapter two which is based on our work in (24) is devoted introducting weighted semigroups (s, w), and studying some famous function spaces on them, especially the relations between go (s, w) and other function speces are invesigated. in fact this chapter is a complement to (32). one of the main fea...
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ژورنال
عنوان ژورنال: Microbiological Reviews
سال: 1989
ISSN: 0146-0749
DOI: 10.1128/mmbr.53.4.410-449.1989